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Medical Studies/Proven Research

Nathan Pritikin Research Foundation Bibliography - Published Research Articles

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NATHAN PRITIKIN FOUNDATION

Nathan Pritikin Research Foundation

For the past 30 years, the Nathan Pritikin Research Foundation has published more than 100 studies documenting the extraordinary benefits of the Pritikin Program. It is research that persistently proves to doctors, health institutions, and the media that we can halt many of modern society’s diseases, rapidly and economically, with good nutrition and exercise. It is research that saves lives.
Nathan Pritikin Research Foundation

Scientifically Proven Results

Since 1975, more than 100,000 guests have experienced the life-changing benefits of the Pritikin Longevity Center® & Spa. Nearly 10 million have read the nine best-selling books on the Pritikin Program. Most importantly, no other diet-and-exercise program has been more highly praised by the scientific community. More than 100 studies in top medical journals have found that people who adopt the Pritikin Program achieve dramatic results in just a few weeks, with more benefits long-term. The Pritikin Program has been proven to:

Markedly Reduce Risk Factors For Heart Disease

Cholesterol: Analyses of 4,587 guests staying at Pritikin for three weeks showed an average 23% drop in total cholesterol and 23% drop in LDL "bad" cholesterol. New England Journal of Medicine, 323: 1142, 1990; Archives of Internal Medicine, 151: 1389, 1991. See also Circulation, 106: 2530, 2002.

Triglycerides: These 4,587 Pritikin guests also reduced triglycerides on average 33%. New England Journal of Medicine, 323: 1142 ,1990; Archives of Internal Medicine, 151: 1389, 1991.

C-Reactive Protein: In just two weeks, inflammation markers like C-reactive protein plummeted 45% in women at the Pritikin Center. No other diet-and exercise program or drug therapy, including statins, has proven to lower C-reactive protein so dramatically or rapidly. Metabolism, 53: 377, 2004.

Insulin: In three weeks, insulin levels fell 46% in men at the Pritikin Center. Circulation, 106: 2530, 2002.

Metabolic Syndrome: Having the Metabolic Syndrome, a condition now epidemic in the U.S., puts one at major risk for diabetes and heart disease. In about 50% of men studied, the syndrome was not only controlled but also reversed after just three weeks at the Pritikin Center. Journal of Applied Physiology, 100: 1657, 2006.

Lower Blood Pressure to Normal, Medication-Free Levels

In a study of 268 men, 83% lowered their blood pressure to normal levels and left free of all drugs for hypertension. Journal of Cardiac Rehabilitation, 3: 839, 1983. See also Circulation, 106: 2530, 2002.

Enhance Effectiveness of Statin Therapy

Prior to attending Pritikin, 93 people had reduced their cholesterol about 20% on statins. After two weeks at Pritikin, they demonstrated an additional 19% decrease in cholesterol. American Journal of Cardiology, 79: 1112, 1997.

Control Diabetes and, for Many, Eliminate the Need for Drugs

A meta-analysis of 864 diabetics found that 74% on oral agents left Pritikin free of such medications; and 44% on insulin left insulin-free. Those who continued the Pritikin Program stayed off the medications. Journal of Applied Physiology,98: 3, 2005. See also Diabetes Care, 17: 1469, 1994.

Promote Healthy, Long-Term Weight Loss

Pritikin Guests in need of weight loss lose 12 pounds and more within three weeks of starting Pritikin. Archives of Internal Medicine, 151: 1389, 1991.

In two long-term studies, more than 85% of Pritikin graduates claimed a 50% or greater adherence to the Pritikin Program after 5 years, and the majority continued to lose weight after leaving the Center. Journal of Cardiac Rehabilitation, 3: 183, 1983; Diabetes Care, 6: 268, 1983.

The most comprehensive study of long-term weight loss ever conducted, the National Weight Control Registry, found that the vast majority of its nearly 4,500 successful dieters follow a diet, like Pritikin, that is low in fat and very high in fiber-rich carbohydrates like fruits and vegetables. The members lost, on average, 66 pounds and have kept it off for six years. Less than 1% follow a high-protein, high-fat diet. Journal of the American Dietetic Association, 98: 480, 1998.

Eliminate the Need for Angioplasty and Bypass Surgery; Relieve Angina Pain

A five-year follow-up of 64 participants who went to Pritikin instead of having bypass surgery found that 80% never needed surgery. Of those taking drugs for angina (chest) pain, 62% left the Center pain-free and drug-free. Journal of Cardiac Rehabilitation, 3: 183, 1983.

Mitigate the Metabolic Syndrome

High insulin levels, high blood pressure, high triglycerides, and obesity commonly aggregate in the same individual and greatly increase the risk for coronary disease. The Pritikin Program controlled this syndrome in just three weeks in a majority of 72 people studied. Fasting insulin was reduced by 30-40%. American Journal of Cardiology, 69: 440, 1992. See also Journal of Applied Physiology, 100: 1657, 2006.

Among children studied who had the Metabolic Syndrome, 100% reversed the syndrome within two weeks of adopting the Pritikin Program. Metabolism, 2006.

Reduce Key Risk Factors for Breast, Colon, and Prostate Cancer

Several studies have found that adopting the Pritikin Program reduced key risk factors for breast, colon, and prostate cancer. Journal of the National Cancer Institute, 86: 1419, 1994; Nutrition and Cancer, 31: 127,1998; Nutrition and Cancer, 38: 158, 2000; The Journal of Urology, 166: 1185, 2001.

Groundbreaking studies also showed that the Pritikin Program retarded the growth of both breast cancer and prostate cancer cells in in vitro laboratory testing, and even induced tumor cells to self-destruct. Prostate, 56: 201, 2003; Nutrition and Cancer, 2006

In 2005, scientists also reported that men with prostate cancer were able to avoid aggressive treatment, surgery, radiation, etc., by exercising regularly, increasing their fruit-and-vegetable intake, and reducing dietary fat to 10% of total calories. Journal of Urology, 174:1065, 2005

Promote Smoking Cessation

The customized smoking cessation program at Pritikin has helped many guests quit smoking for good. Plus, their new Pritikin lifestyles helped ensure that they did not gain weight while quitting. Many, in fact, lost weight.

2007

Sullivan S, Klein S. Effect of a short-term Pritikin diet therapy on the metabolic syndrome. J CardioMetab Syndrome. 1:308-312,2006

Roberts, C.K., A.K. Chen, R.J. Barnard. Effect of a short-term diet and exercise intervention in youth on atherosclerotic risk factors. Atherosclerosis 191:98-106,2007

Dewell, A., G. Weidner, M.D. Sumner, R.J. Barnard, R.O. Marlin, J.J. Daubenmier, P.R. Carroll, D. Ornish. Evaluation of dietary protein and soy isoflavones in relation to serum IGF-I and IGF binding proteins in the Prostate Cancer Lifestyle Trial. Nutrition and Cancer 58:35-42,2007

Barnard, R.J. P.S. Leung, W.J. Aronson, P. Cohen, L.A. Golding. A mechanism to explain how regular exercise might reduce the risk for clinical prostate cancer. The European Journal of Cancer Prevention 16:415-421, 2007

Barnard, R.J. Prostate cancer prevention by nutritional means to alleviate metabolic syndrome. The American Journal of Clinical Nutrition 86(suppl):889S-893S,2007

2006

Booth, F.W., and M.V. Chakravarthy. Physical activity and dietary intervention for chronic diseases: a quick fix after all? J. Appl. Physiol. (Invited Editorial) 100:1439-1440, 2006.

Roberts, C.K., D. Won, S. Pruthi, S. Kurtovic, R.K. Sindhu, N.D. Vaziri, R.J. Barnard. Effect of a short-term diet and exercise intervention on oxidative stress, inflammation, MMP-9 and monocyte chemotactic activity in men with metabolic syndrome factors. J Appl Physiol 100:1657-1665, 2006 - Download PDF

Chen, A., C.K. Roberts and R.J. Barnard. Effect of a short-term diet and exercise intervention on metabolic and anthropometric parameters in overweight children and adolescents. Metabolism 55:871-878,2006

Roberts, C.K., R.J. Barnard, R.K. Sindhu, M. Jurczak, A. Ehdaie, N.D. Vaziri. Oxidative stress and dysregulation of NAD(P)H oxidase and anitoxidant enzymes in diet-induced metabolic syndrome. Metabolism 55:928-934,2006

Roberts, C.K., D. Won, S. Pruthi, R.J. Barnard Effect of diet and exercise intervention on oxidative stress, inflammation and monocyte adhesion in diabetic men. Diabetes Res. 73:249-259,2006

Barnard, R.J., J.H. Gonzalez, M. Liva, T.H. Ngo. Effect of a low-fat, high-fiber diet and exercise program on breast cancer risk factors in vivo and tumor cell growth and apoptosis in vitro. Nutrition and Cancer 55:28-34,2006

Roberts, C.K., C. Ng, S. Hama, R.J. Barnard. Effect of a diet and exercise intervention on inflammatory/anti-inflammatory properties of HDL in men with cardiovascular risk factors. J. Appl. Physiol. 101:1727-1732,2006

Sullivan S, Klein S. Effect of a short-term Pritikin diet therapy on the metabolic syndrome. J Cardio Metab Syndrome. 1:308-312, 2006.

2005

Roberts, C.K., R.J. Barnard, R.K. Sindhu, M. Jurczak, A. Ehdaie, N.D. Vasiri. A high-fat, refined carbohydrate diet induces endothelial dysfunction, oxidant/antioxidant imbalance and depresses NO synthase protein expression. J Appl Physiol 98:203-210, 2005.

Barnard, R.J. and W.J. Aronson. Preclinical models relevant to diet, exercise, and cancer. In: Recent Results in Cancer Research (Controversies in Tumor Prevention and Genetics III). H-J. Senn and R. Morant, eds. Springer 2005, 166:47-62.

Roberts, C.K. and Barnard, R.J. Effect of diet and exercise on chronic disease. J Appl Physiol 98:3-30, 2005.

Ornish D, Carroll PR, Fair WR, Pettengill EB, Marlin R, Raisin CJ, Dunn-Emke S, Crutchfield L, Barnard RJ, McCormac P, McNight DJ, Fein JD, Dnstrian AM, Weinstein J, Ngo T, Weidner G. Intensive lifestyle changes may affect the progression of prostate cancer. J Urol 174:1065-1070, 2005.

2004

Ngo, T.H., R.J. Barnard, T. Anton, C. Tran, D. Elashoff, D. Heber, S.J. Frieedland and W.J. Aronson. Effect of isocaloric low-fat diet on prostate cancer xenograft progression to androgen independence. Cancer Res. 64:1252-1254, 2004.

Wegge, J.K.,C.K. Roberts,T.H. Ngo and R.J. Barnard. Effect of diet and exercise intervention on inflammatory markers of atherosclerosis in postmenopausal women. Metabolism 53:377-381, 2004.

Molteni, R., A. Wu, S. Vaynmam, R.J.Barnard and F.Gomez-Pinilla. Voluntary physical activity compensates for the deleterious effects of a high-fat, refined-sugar diet on behavioral and neuronal plasticity. Neuroscience 123:429-440, 2004.

Leung, P-S.,W.J. Aronson,T.H. Ngo, L.A. Golding and R.J. Barnard. Exercise alters the IGF axis in vivo and increases p53 protein in prostate tumor cells in vitro. J. Appl. Physiol. 96:450-454, 2004.

Roberts, C.K. K. Liang, R.J. Barnard, C.H. Kim and N.D. Vaziri. HMG-CoA reductase, cholesterol 7a-hydroxylase, LDL receptor, SR-B1, and ACAT in diet-induced syndrome X. Kidney International 66:1503-1511, 2004.

Barnard, R.J. and Aronson, W.J. Diet, Exercise and Prostate Cancer. In: Prostate Cancer, J.N. Lucas ed. Nova Science, Hauppauge, N.Y. Chapt. I, 2004.

Barnard, R.J. Prevention of cancer through lifestyle changes. eCAM Jol 1:233-239, 2004.

2003

Ngo, T.H., R.J. Barnard, P. Cohen, S. Freedland, C. Tran, F. deGregorio, Y.I. Elshimal, D. Heber and W.J. Aronson. Effect of isocaloric low-fat diet on human LAPC-4 prostate xenografts and the IGF axis in SCID mice. Clin. Cancer Res 9:2734,2003

Roberts, C.K. and R.J. Barnard. Low-carbohydrate diets as compared with low-fat diets. New Engl J Med 349:1000,2003

Barnard, R.J. and J.O. Holloszy. The metabolic systems: Aerobic metabolism and substrate utilization in exercising skeletal muscle. in: The History of Exercise Physiology. C.M. Tipton editor, Oxford Press, New York, NY. p 292-320, 2003

Roberts, C.K., N.D. Vaziri, R.K. Sindhu and R.J. Barnard. A high-fat, refined carbohydrate diet affects renal NO synthase protein expression and salt sensitivity. J Appl. Physiol 94:941-946,2003

J.J. Kenney and J.S. Novick. Optimal diets to prevent heart disease. JAMA 289:1510, 2003

Barnard, R.J., T.H. Ngo, W.J. Aronson and L.A. Golding. A low-fat diet and/or strenuous exercise alters the IGF axis in vivo and reduces prostate tumor cell growth in vitro. Prostate 56:201-206,2003

Ngo, T.H., R.J. Barnard, P. Cohen and W.J. Aronson. IGF-1 and Insulin-like growth factor binding protein-1 (IGFBP-1) modulate prostate cancer cell growth and apoptosis: Possible mediators for the effects of diet and exercise on cancer cell survival. Endocrinology 144:2319-2324,2003

2002

Roberts, C.K., N.D. Vaziri, R.J. Barnard. Effect of diet and exercise intervention on blood pressure, insulin oxidative stress, and nitric oxide availability. Circulation 106:2530-2532,2002

Roberts, C.K., R.J. Barnard, K.H. Lui and N.D. Vaziri. Effect of diet on adipose tissue and skeletal muscle VLDL receptors and LPL: Implications for obesity and hyperlipidemia. Atherosclerosis 161:133-141,2002

Roberts. C.K., N.D. Vaziri, Z. Ni, X.Q. Wang and R.J. Barnard. Correction of long-term diet-induced hypertension and protein nitration by diet modification. Atherosclerosis 163:321-327,2002

Molteni, R., R.J. Barnard, Z. Ying, C.K. Roberts and F. Gomez-Pinilla. A high-fat, refined-sugar diet reduces BDNF, neuronal plasticity, and cognitive function. Neuroscience 112:803-814,2002

Tymchuk, C.N., R.J. Barnard , T.H. Ngo and W.J. Aronson. The role of testosterone, estradiol, and insulin in diet and exercise-induced reductions in prostate cancer cell growth. Nutrition and Cancer 42 (1):  112-116, 2002

Roberts, C.K., J.J. Berger and R.J. Barnard. Long-term effects of diet on leptin, energy intake and activity in a model of diet-induced obesity. J.Appl. Physiol. 93:887-893,2002

Ngo, T.H., R.J. Barnard, C.N. Tymchuk, P. Cohen. And W.J. Aronson. Effect of diet and exercise on serum insulin, IGF-1, and IGFBP-1 levels and growth of LNCaP cells in Vitro. Cancer Causes & Control 13:929-935,2002

Barnard, R.J., W.J. Aronson, C.N. Tymchuk and T.H. Ngo. Prostate cancer: Another aspect of the insulin resistance syndrome. Obesity Rev 3:303-308,2002

Barnard, R.J. and J.O. Holloszy. The metabolic systems: Aerobic metabolism and substrate utilization in exercising skeletal muscle. in: The History of Exercise Physiology. C.M. Tipton editor, Oxford Press, New York, NY. p 292-320, 2002

2001

Roberts, C.K., N.D. Vaziri. Effects of estrogen on gender specific development of diet-induced hypertension. J. Appl Physiol. 91:2005-2009,2001

Roberts, C.K., N.D. Vaziri, K.H. Liag and R.J. Barnard. Reversibility of long-term diet induced insulin resistance and metabolic syndrome characteristics. Hypertension 37:1323-1328,2001

Youngren, J.F., J.Paik and R.J. Barnard. Impaired insulin receptor autophosphorylation is an early defect in fat-fed, insulin-resistant rats. J. Appl. Physiol. 91:2240-2247,2001

Tymchuk, C.N., S.B. Tessler and R.J. Barnard. Changes in sex hormone-binding globulin, insulin and serum lipids in postmenopausal women on a low-fat, high-fiber diet combined with exercise. Nutrition and Cancer 38:158-162,2000

Tymchuk, C.N., R.J. Barnard, D. Heber and W.J. Aronson. Evidence for an inhibitory effect of diet and exercise on prostate cancer cell growth. J. Urol . 166:1185-1189,2001

2000

Barnard, R.J. American College of Sports Medicine Position Stand on Exercise and Type 2 Diabetes. Am. J. Med. Sports 2:364-367,2000

Roberts, C.K., N.D. Vaziri, X.Q. Wang, and R.J. Barnard. NO inactivation and hypertension induced by a high-fat, refined carbohydrate diet. Hypertension 36:423-429,2000

Fonseca, V., A. Dicker-Brown, S. Ranganathan, W. Song, R.J. Barnard, L. Fink and P.A. Kern. Effect of a high-fat-sucrose diet on enzymes of homocysteine metabolism in the rat. Metabolism 49:736-741,2000

1999

Barnard, R.J. The role of exercise in the detection and treatment of peripheral vascular disease. In. Exercise and the Heart in Health and Disease . R. J. Shephard and H.S. Miller eds. Marcel Dekker, Inc. New York, N.Y. , 1999

Barnard, R.J. and S.B. Inkeles. Effects of an intensive diet and exercise program on lipids in postmenopausal women. Women's Health Issues 9:155-161,1999

Reil, T.D., R.J. Barnard, V.S. Kashyap, C.K. Roberts and H.A. Gelabert. Diet induced changes in endothelial dependent relaxation of the rat aorta. J Surg Res 85:96-100,1999

Berger, J.J. and R.J. Barnard. Effect of diet on fat cell size and hormone sensitive lipase activity. J Appl Physiol. 87:227-232,1999

Barnard, R.J. A carbohydrate diet to prevent and control coronary heart disease. Pritikin was Right. ACSM's Health and Fitness J. 3:23-26,1999

Roberts, C.K., R.J. Barnard, A. Jasman and T.W. Balon. Acute exercise increases nitric oxide synthase activity in skeletal muscle. Am J Physiol 277 (Endocrinol. Metab 40 ) E390-E394,1999

Kenney, J.K., R.J. Barnard and S. Inkeles. Very-low-fat diets do not necessarily promote small, dense LDL particles. Am J Clin Nutr. 70:423,1999

Barnard, R.J. and S.B. Inkeles. The value of lifestyle change in treating coronary disease - what does it take? Preventive Cardiology 2:159-163,1999

Barnard, R.J. Very-low-fat diets . Circulation 100:1012-1013,1999

1998

Barnard, R.J., C.K. Roberts, S.M. Varon and J.J. Berger, Diet-induced insulin resistance precedes other aspects of the metabolic syndrome. J Appl Physiol, 84:1311-1315,1998

Tymchuk, C.N., S.B. Tessler, W.J. Aronson and R.J. Barnard, Effects of diet and exercise on insulin, sex hormone-binding globulin and prostate-specific antigen. Nutrition and Cancer, 31:127-131,1998

1997

Barnard, R.J., J.F. Youngren and S.H. Scheck, Reversibility of diet-induced skeletal muscle insulin resistance. Diabetes Res, 32:213-221,1997

Barnard, R.J., S.C. DiLauro and S.B. Inkeles, Effects of intensive diet and exercise intervention in patients taking cholesterol-lowering drugs. Am J Cardiol 79:1112-1114,1997

Roberts, C.K., R.J. Barnard, S.H. Scheck and T. W. Balon, Exercise-stimulated glucose transport in skeletal muscle is nitric oxide dependent. Am J Physiol 273:E220-E225,1997

1996

Beard, C.M., R.J. Barnard, D.C. Robbins, J.M. Ordovas and E.J. Schaefer, Effects of diet and exercise on qualitative and quantitative measures of LDL and its susceptibility to oxidation. Arterioscler Thromb Vasc Biol, 16:201-207,1996

1995

Bagga, D., J.M. Ashley, S.P. Geffrey, H-J. Wang, R.J. Barnard, S. Korenman and D. Heber, Effects of a very low fat, high fiber diet on serum hormones and menstrual function: Implications for breast cancer prevention. Cancer, 76:2491-2496,1995

Zernicke, R.F., G.J. Salem, R.J. Barnard, J.S. Woodward Jr., J.W. Meduski and J.D. Meduski, Adaptations of immature trabecular bone to exercise and augmented dietary protein. Med Sci Sports Exer, 27:1486-1493,1995

Li, K-C, R F. Zernicke, R.J. Barnard and A.F-Y. Li, Response of immature diabetic bone-ligament junctions to insulin and exercise. Clin Biomech, 10 : 331-336,1995

Barnard, R.J., J.F. Youngren and D.A. Martin, Diet, not aging, causes skeletal muscle insulin resistance. Gerontology, 41:205-211,1995

Czernin, J., R.J. Barnard, K.T. Sun, J. Krivokapich, E. Nitzsche, D. Dorsey, M.E. Philps and H.R. Schelbert, Effect of short-term cardiovascular conditioning and low-fat diet on myocardial blood flow and flow reserve. Circulation, 92:197-204,1995

Zernicke, R.F., G.J. Salem, R J. Barnard and E. Schramm, Long-term, high-fat-sucrose diet alters rat femoral neck and vertebral morphology, bone mineral content, and mechanical properties. Bone, 16:25-31,1995

Youngren, J.F. and R.J. Baranard, Effects of acute and chronic exercise on skeletal muscle glucose transport in aged rats. J Appl Physiol, 78,1750-1756,1995

1994

Barnard, R.J., T. Jung and S.B. Inkeles, Diet and exercise in the treatment of NIDDM - the need for early emphasis. Diabetes Care, 17:1469-1472,1994

Bagga, D., J.M. Ashley, S. Geffrey, Hei-Jung, R.J. Barnard, R. Elashoff and D. Heber, Modulation of serum and breast duct fluid lipids by a very low-fat, high-fiber diet in premenopausal women. JNCI, 86:1419-1421,1994

Barnard, R.J. and, S.J. Wen, Exercise and diet in the prevention and control of the metabolic syndrom. Med Sports 18:218-228,1994

Barnard, R.J., Physical activity, fitness and claudication. In Physical Activity, Fitness and Health 1992 Proceedings. C. Bouchard, R.J. Shephard and T. Stephens, eds. Human Kinetics, Champaign, IL. p 622-632, 1994.

1993

Li, K.C., R. F. Zernicke, R.J. Barnard, A.F.X. Li, P. Campbell. Effects of mild diabetes on immature cortical bone. Clin Biomech, 8:49-51,1993

Barnard, R.J., D.J. Faria, J.E. Menges, and D.A. Martin, Induction of hyperinsulinemia and related atherosclerotic risk factors by a high-fat, sucrose diet. Atherosclerosis, 100: 229-239, 1993.

Li, K-C, R.F. Zernicke, R.J. Barnard and A.F-Y Li. Response of immature bone-ligament junction to a high-fat, sucrose diet. Clin Biomech, 8:163-165, 1993

Hou. J. C-H., R.F. Zernicke, and R.J. Barnard. Effects of severe diabetes on immature rat femoral neck. J Orthop Res, 11: 263-271, 1993.

1992

Salem, G.J., R.F. Zernicke, R.J. Barnard. Diet related changes in mechanical properties or rat vertebrae. Am J Physiology, 262:R318-R321,1992

Barnard, R.J., E.J. Ugianskis, D.A. Martin. The effect of an intensive diet and exercise program on patients with NIDDM and hypertension. J Cardioresp Rehab, 12:194-201, 1992

Barnard, R.J., L.O. Lawani, D.A. Martin, J.F. Youngren, R. Singh, S.H. Scheck. Effects of maturation and aging on the skeletal muscle glucose transport system. Am J Physiol, 262:E619-E626, 1992

Barnard, R.J. Response to "Letter to the Editor". Arch Intern Med, 152:1721-1723,1992

Barnard, R.J., E.J. Ugianskis, D.A. Martin, S.B. Inkeles. Role of diet and exercise in the managment of hyperinsulenemia and related atherosclerotic risk factors. Am J Cardiol, 69:440-444,1992.

1991

Li, K-C., R.F. Zernicke, R.J. Barnard and A. F-Y Li. Differential response of rat limb bones to strenuous exercise. J Appl Physiol, 70:554-560,1991.

Scheck, S.H., R.J. Barnard, L.O. Lawani, J.F. Youngren, D.A. Martin and R. Singh. Effects of NIDDM on the glucose transport system in human skeletal muscle. Diabetes Res, 16:111-119,1991.

Barnard, R.J. Effects of life style modification on serum lipids. Arch Int Med, 151:1389-1394,1991.

Hou, J.C-H., R.F. Zernicke and R.J. Barnard. Experimental diabetes, insulin treatment and femoral neck morphology and biomechanics in rats . Clin Orthop, 264:278-85,1991.

Heber, D., J.A. Ashley, D.A. Leaf, R.J. Barnard. Reduction in serum estrodiol in postmenopausal women given free access to a low-fat, high-carbohydrate diet. Nutrition, 7:137-40,1991.

1990

Barnard, R.J. Use of exercise and diet to fight peripheral vascular disease; Your Patient and Fitness, 5:12-16,1990.

Barnard, R.J., D. S. Kartel, J.F. Youngren and D.A. Martin. Effects of streptozotocin-induced diabetes on glucose tramsport in skeletal muscle. Endocrinology, 126:1921-1926,1990.

Barnard, R.J. Serum lipid reductions achieved with diet and exercise. New Engl J Med, 323:16,1990.

Hou, J.C-H., R.F. Zernicke and R.J. Barnard. High-fat sucrose diet effects in femoral neck geometry and biomechanics. Clin Biomech, 5:162,1990.

Hou, J. C-H, G.J. Salem, R.F. Zernicke and R.J. Barnard. Structural and mechanical adaptations of immature trabecular bone to strenuous exercise. J Appl Physiol, 69:1309-1314,1990.

Li, K-C, R.R. Zernicke, R.J. Barnard and A. F-Y Li. Effects of a high-fat, sucrose diet on cortical bone remodeling and biomechanics. Calcif Tissue Int, 47:308-313,1990.

Mehrabian, M., J. Peter, R.J. Barnard and A. Lusis. Dietary regulation of fibrinolytic factors. Atherosclerosis, 84:24,1990.

1989

Kenney, J., M. Rosenthal, S. Inkeles and R.J. Barnard. Letter to the Editor. New Engl J Med , 320: 536,1989.

Sternlicht, E., R.J. Barnard and G.K. Grimditch. Exercise and insulin stimulate skeletal muscle glucose transport through different mechanisms. Am J Physiol, 256: E227-E320,1989.

Sternlicht, E., R.J. Barnard and G.K. Grimditch. B-adrenergic receptors are not responsible for exercise stimulation of glucose transport. J Appl Physiol, 66:2419-2422,1989.

1988

Barnard, R.J. and J.A. Hall. The role of exercise in the detection, treatment and evaluation of patients with peripheral vascular disease; in Exercise and Modern Medicine: Testing and Prescription in Health and Disease. B.A. Franklin, S. Gordon, G.C. Timmis, eds, Williams & Wilkins, Baltimore, MD.,1988

Barnard, R.J., J.B. Peter, J. Hall and C. Kinsella. Effects of a short-term diet and exercise program on serum apoproteins. J Appl Nutr, 40:5-12,1988.

Barnard, R.J., R. Pritikin, R. Rosenthal and S. Inkeles. Pritikin Approach to Cardiac Rehabilitation; Rehabilitation Medicine, J. Goodgold, ed., C.V. Mosby Company, St. Louis, MO.,1988

Grimditch, G.K., R.J. Barnard, L. Hendricks and D. Weitzman. Peripheral insulin sensitivity as modified by diet and exercise training. Am J Clin Nutr, 48:38-43,1988.

Reddy, B. S., A. Engle, B. Simi, L.T. O'Brien, R.J. Barnard, N. Pritikin and E. L. Wynder. Effect of low-fat, high carbohydrate, high-fiber diet on fecal bile acids and neutral sterols . Preventive Med ,17:432-439, 1988.

Sternlicht, E., R.J. Barnard and G.K. Grimditch. Mechanism of insulin action on glucose transport in rat skeletal muscle. Am J Physiol, 254:E633-E638:1988.

Whitson, R.H., G.K. Grimditch, E. Sternlicht, S.A. Kaplan, R.J. Barnard and K. Itakura. Characterization of rat skeletal muscle sarcolemmal insulin receptors and a sarcolemmal insulin binding inhibitor; J Biol Chem, 263:4789-4794,1988.

1987

Barnard, R.J., J.A. Hall, A. Chaudhari, J.E. Miller and M.A. Kirschenbaum. Effects of low-fat, low-cholesterol diet on serum lipids, platelet aggregationand thromboxane formation. Prostaglandins Leukotrienes and Medicine, 26:241-252,1987.

Barnard, R.J., S. Inkeles and K.A. Foon. Nathan Pritikin's Heart. Nutrition Today, 22:39,1987.

Grimditch, G.K., RJ. Barnard, E. Sternlicht, R.H. Whitson and S.A. Kaplan. Effect of diet on insulin binding and glucose transport in rat sarcolemmal vesicles. Am J Physiol, 252: E420-E425, 1987.

1986

Grimditch, G.K., R.J. Barnard, S.A . Kaplan and E. Sternlicht. Effect of training on insulin binding to rat skeletal sarcolemmal vesicles. Am J Physiol, 250: E570-E575, 1986.

Holly, R G., R.J. Barnard, M. Rosenthal, E. Applegate and N. Pritikin. Triathlete characterization and response to prolonged strenuous competition. MedSci Sports Exerc, 18:123-127,1986.

1985

Barnard, R.J., J.A. Hall and N. Pritikin. Effects of diet and exercise on blood pressure and viscosity in hypertensive patients. J Cardiac Rehab, 5: 185-190, 1985.

Barnard, R.J. Research at the Pritikin Longevity Center. J Applied Cardiol, Nov/Dec: 8-12, 1985.

Giardina, S.L., R.W. Schroff, C.S. Woodhouse, D.W. Golde, R.K. Oldham, M.L. Cleary, J. Sklar, N. Pritikin and K.A. Foon. Detection of two distinct malignant B cell clones in a single patient using anti-idiotype monoclonal antibodies and immunoglobulin gene rearrangement. Blood , 66: 1017-1021,1985.

Grimditch, G.K., R.J. Barnard, S.A. Kaplan and E. Sternlicht. Insulin binding and glucose transport in rat skeletal muscle sarcolemmal vesicles. Am J Physiol, 249: E398-E408, 1985.

Hubbard, J.D., S. Inkeles and R.J. Barnard. Nathan Pritikin's Heart. N Engl J Med, 313:52, 1985.

O'Brien, L.T., R.J. Barnard, J.A. Hall and N. Pritikin. Effects of a high-complex-carbohydrate low-cholesterol diet plus bran supplement on serum lipids. J Appl Nutr, 37: 26-34, 1985.

Rosenthal, M.B., R.J. Barnard, D.P. Rose, S. Inkeles, J. Hall and N. Pritikin. Effects of a high-complex-carbohydrate, low-fat, low-cholesterol diet on levels of serum lipids and estradiol. Amer J Med , 78: 23-27, 1985

1983

Barnard, R.J., P. Guzy, J. Rosenberg and L.T. O'Brien. Effects of an intensive exercise and nutrition program on patients with coronary artery disease: a five-year follow-up. J Cardiac Rehab, 3: 183-190, 1983.

Barnard, R.J., M.R. Massey, S. Cherney, L.T. O'Brien and N. Pritikin. Long-term use of a high-complex-carbohydrate, high-fiber, low-fat diet and exercise in the treatment of NIDDM patients. Diabetes Care, 6: 268-273, 1983.

Barnard, R.J., S. M. Zifferblatt, J. M. Rosenberg and N. Pritikin. Effects of a high-complex-carbohydrate diet and daily walking on blood pressure and medication status of hypertensive patients. J Cardiac Rehab, 3: 839-846, 1983.

Weber, F., R.J. Barnard and D. Roy. Effects of a high-complex-carbohydrate low-fat diet and daily exercise on individuals 70 years of age and older. J Gerentology , 38: 155-161, 1983.

1982

Barnard, R.J., L. Lattimore, R G. Holly, S. Cherny and N. Pritikin. Response of non-insulin-dependent diabetic patients to an intensive program of diet and exercise; Diabetes Care, 5: 370-374, 1982.

Dintenfass, L. Effect of a low-fat, low-protein diet on blood viscosity factors in patients with cardiovascular disorders. Med.J Australia , 1:543, 1982.

Hall, J.A. and R.J. Barnard. The effects of an intensive 26-day program of diet and exercise on patients with peripheral vascular disease. J Cardiac Rehab, 2: 569-574, 1982.

Hall, J.A., G.H. Dixson, R.J. Barnard and N. Pritikin. Effects of diet and exercise on peripheral vascular disease. Physician Sports Med, 10: 90-101, 1982.

Pritikin, N. Optimal dietary recommendations: a public health responsibility. Preventive Med , 11: 733-739, 1982.

1981

Barnard, R.J., F. Weber, W. Weingarten, C.M. Bennett and N. Pritikin. Effects of an intensive, short-term exercise and nutrition program on patients with coronary heart disease. J Cardiac Rehab, 1: 99-105, 1981.

 


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